Talk:Cyclooxygenase-2 inhibitor

External links modified

Hello fellow Wikipedians,

I have just modified one external link on COX-2 inhibitor. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit User:Cyberpower678/FaQs#InternetArchiveBot*this simple FaQ for additional information. I made the following changes:

• Added archive http://web.archive.org/web/20080509195022/http://www.cancer.gov/cancertopics/factsheet/APCtrialCOX2QandA to http://www.cancer.gov/cancertopics/factsheet/APCtrialCOX2QandA

When you have finished reviewing my changes, please set the checked parameter below to true or failed to let others know (documentation at {{Sourcecheck}}).

This message was posted before February 2018. After February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than regular verification using the archive tool instructions below. Editors have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the RfC before doing mass systematic removals. This message is updated dynamically through the template {{source check}} (last update: 5 June 2024).

• If you have discovered URLs which were erroneously considered dead by the bot, you can report them with this tool.
• If you found an error with any archives or the URLs themselves, you can fix them with this tool.

Cheers.—^{cyberbot II}_{Talk to my owner:Online} 13:38, 9 June 2016 (UTC)

Needs better balance

This article passes over much of the information about COX-2 inhibitors quickly, then spends the bulk of its wordage on *potential* uses + controversy/fraud/etc and I find this odd. It ought to look more like the wikipedia entry for NSAID with a more thorough introductory description, examples, uses, mechanism of action, adverse effects, contraindications. I don't have the time or energy to do this hence I'm just adding my 2 cents to the talk page.Niccast (talk) 23:31, 19 March 2020 (UTC)

Wiki Education assignment: Biochemistry II

This article was the subject of a Wiki Education Foundation-supported course assignment, between 17 January 2022 and 20 May 2022. Further details are available on the course page. Student editor(s): Cayley P (article contribs).

Apoptosis

The last two paragraphs reference apoptosis, a well known biological function of programmed cell death. But the wording is a little too dramatic, in my opinion:

"Coxibs such as Celebrex (celecoxib), by selectively inhibiting the overexpressed COX-2, allow p53 to work properly. Functional p53 allows DNA damaged neuroblastoma cells to commit suicide through apoptosis, halting tumor growth."

Also, this really ought to link to apoptosis, rather than suicide. ThreeRocks (talk) 03:05, 30 September 2022 (UTC)